Adam Devine
Ed (voice)
Rachel Bloom
Op (voice)
Zazie Beetz
Dottie (voice)
Ken Jeong
Clarance (voice)
Jim Jefferies
Burnie (voice)
Catherine O'Hara
Alma (voice)
Reggie Watts
Hoss / Ernest Shackleton (voice)
Henry Winkler
Jepson (voice)
Alex Borstein
Mali (voice)
Benedict Wong
Dr. Chung (voice)
Julia Chan
Mrs. Sun / Little Girl (voice)
Tom Hollander
Charles Darwin (voice)
Richard Kind
Wally (voice)
Steve Aoki
Vinny (voice)
Nick Frost
Captain (voice)
Jon Lovitz
Conch (voice)
Sydney Liu
Bo (voice)
Maria Bamford
Bo's Mom (voice)
Raymond S. Persi
That Guy / Booby (voice)
Terry Gross
Bomb (voice)
David Silverman
Cyclops / Donut Store Clerk (voice)
Kelly Hu
News Reporter (voice)
Tom Kenny
Mozart / Sled Dogs (voice)
Jason Hightower
Narrator / Sled Dogs (voice)
Kevin Michael Richardson
Sled Dogs (voice)
Brenden P. Hill
Baseball Announcer (voice)